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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2074
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ahr
Name: aryl hydrocarbon receptor
Acc ID: CHEBI:28073
Term: chromium atom
Definition: A chromium group element atom that has atomic number 24.
Chemical ID: MESH:D002857
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ahrmultiple interactionsISOAhr (Mus musculus)6480464CTD[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Butyrates inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]PMID:17682057
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