GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agt | affects metabolic processing | ISO | Agt (Mus musculus) | 6480464 | CTD | Thiorphan affects the metabolism of AGT protein | PMID:27649628 | Agt | multiple interactions | ISO | Agt (Mus musculus) | 6480464 | CTD | [[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [[Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein; [Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein; [Thiorphan affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); ACE2 protein affects the reaction [[[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7)]; S 17092-1 promotes the reaction [Thiorphan inhibits the reaction [AGT protein results in increased abundance of angiotensin I (1-7)]]; Thiorphan inhibits the reaction [[Lisinopril affects the metabolism of AGT protein] which results in increased abundance of angiotensin I (1-7)]; Thiorphan inhibits the reaction [AGT protein results in increased abundance of angiotensin I (1-7)]; Thiorphan promotes the reaction [S 17092-1 inhibits the reaction [AGT protein results in increased abundance of angiotensin I (1-7)]] | PMID:27649628 PMID:31786979 | Agt | multiple interactions | ISO | AGT (Homo sapiens) | 6480464 | CTD | [[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [[Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein; [Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein | PMID:27649628 | |
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