Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agt
Name: angiotensinogen
Acc ID: CHEBI:9568
Term: Thiorphan
Definition: A N-acyl-amino acid that has formula C12H15NO3S.
Chemical ID: MESH:D015244
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtaffects metabolic processingISOAgt (Mus musculus)6480464CTDThiorphan affects the metabolism of AGT proteinPMID:27649628
Agtmultiple interactionsISOAgt (Mus musculus)6480464CTD[[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [[Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein; [Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein; [Thiorphan affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); ACE2 protein affects the reaction [[[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7)]; S 17092-1 promotes the reaction [Thiorphan inhibits the reaction [AGT protein results in increased abundance of angiotensin I (1-7)]]; Thiorphan inhibits the reaction [[Lisinopril affects the metabolism of AGT protein] which results in increased abundance of angiotensin I (1-7)]; Thiorphan inhibits the reaction [AGT protein results in increased abundance of angiotensin I (1-7)]; Thiorphan promotes the reaction [S 17092-1 inhibits the reaction [AGT protein results in increased abundance of angiotensin I (1-7)]]PMID:27649628 PMID:31786979
Agtmultiple interactionsISOAGT (Homo sapiens)6480464CTD[[Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [[Lisinopril co-treated with Thiorphan] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7); [Lisinopril co-treated with Thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein; [Lisinopril co-treated with Thiorphan] affects the metabolism of AGT proteinPMID:27649628
Go Back to source page   Continue to Ontology report