GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agt | increases localization | EXP | | 6480464 | CTD | Folic Acid results in increased localization of AGT protein | PMID:15728788 | Agt | multiple interactions | EXP | | 6480464 | CTD | AGT protein promotes the reaction [Folic Acid results in increased expression of PTHLH protein]; candesartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]]; Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]; Losartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]]; Losartan inhibits the reaction [Folic Acid results in increased localization of AGT protein]; PTHLH protein promotes the reaction [Folic Acid results in increased expression of AGT protein] | PMID:15728788 | Agt | decreases expression | ISO | Agt (Mus musculus) | 6480464 | CTD | Folic Acid results in decreased expression of AGT mRNA | PMID:25629700 | Agt | multiple interactions | ISO | Agt (Mus musculus) | 6480464 | CTD | Folic Acid affects the reaction [HPH1 protein affects the susceptibility to AGT protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CBS mRNA]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CBS protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CTH mRNA]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of CTH protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of MTHFR mRNA]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of MTHFR protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of NOS3 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of TIMP1 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of TIMP2 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of TIMP3 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of TIMP4 protein]; Folic Acid inhibits the reaction [AGT protein results in decreased expression of VEGFA protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of and results in increased activity of MMP2 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of and results in increased activity of MMP9 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of COL18A1 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of CYBB protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of DDAH1 mRNA]; Folic Acid inhibits the reaction [AGT protein results in increased expression of DDAH1 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of NOX4 protein]; Folic Acid inhibits the reaction [AGT protein results in increased expression of PLG protein] | PMID:22083158 PMID:24386282 | | ||||||||||||||||||||||
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