GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Parp1 | increases cleavage | ISO | PARP1 (Homo sapiens) | 6480464 | CTD | Aspirin results in increased cleavage of PARP1 protein | PMID:11228543 PMID:11532860 PMID:19595669 PMID:19908241 PMID:9694730 | Parp1 | multiple interactions | ISO | PARP1 (Homo sapiens) | 6480464 | CTD | [Aspirin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; Aspirin inhibits the reaction [Deoxycholic Acid results in increased cleavage of PARP1 protein]; Aspirin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]; Aspirin promotes the reaction [troglitazone results in increased cleavage of PARP1 protein]; Aspirin results in increased cleavage of and results in increased activity of PARP1 protein; BCL2 protein inhibits the reaction [Aspirin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; troglitazone promotes the reaction [Aspirin results in increased cleavage of PARP1 protein] | PMID:15481331 PMID:16199534 PMID:17644113 PMID:18483385 PMID:19908241 | | ||||||||||||||||||||||
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