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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2027
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Actg2
Name: actin gamma 2, smooth muscle
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Actg2decreases expressionEXP 6480464CTDTretinoin results in decreased expression of ACTG2 proteinPMID:16043492
Actg2increases expressionISOACTG2 (Homo sapiens)6480464CTDTretinoin results in increased expression of ACTG2 mRNAPMID:15894607
Actg2multiple interactionsISOActg2 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of ACTG2 mRNA; [bisphenol F co-treated with Tretinoin] results in decreased expression of ACTG2 mRNA; [bisphenol S co-treated with Tretinoin] results in decreased expression of ACTG2 mRNAPMID:30951980
Actg2multiple interactionsISOACTG2 (Homo sapiens)6480464CTD[Tretinoin co-treated with arsenic trioxide] results in increased expression of ACTG2 mRNAPMID:15894607
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