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GENE - TERM ANNOTATION REPORT

RGD ID: 2024
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acr
Name: acrosin
Acc ID: GO:0007340
Term: acrosome reaction
Definition: The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.
Definition Source(s): GOC:dph, PMID:11175768, PMID:21042299, PMID:3886029
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acrinvolved_inISOACR (Homo sapiens)1624291RGD PMID:2550339 PMID:37004249

PMID:2550339 PMID:37004249
Acrinvolved_inIBAPANTHER:PTN000665983 or Acr (Rattus norvegicus) or UniProtKB:P103231600115GO_CentralGO_REF:0000033

GO_REF:0000033
Acrinvolved_inTAS 8553887HGNC-UCLPMID:12398221

 
Acrinvolved_inISSUniProtKB:P103231600115UniProtGO_REF:0000024

GO_REF:0000024
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