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GENE - TERM ANNOTATION REPORT

RGD ID: 18920996
Species: Heterocephalus glaber
RGD Object: Gene
Symbol: Il18
Name: interleukin 18
Acc ID: DOID:9675
Term: pulmonary emphysema
Definition: A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls. (DO)
Definition Source(s): https://my.clevelandclinic.org/health/diseases/9370-emphysema "DO" "DO", https://www.cedars-sinai.org/health-library/diseases-and-conditions/p/pulmonary-emphysema.html "DO" "DO", https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=85&contentid=p01309 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il18 ISOIl18 (Rattus norvegicus)9068941RGDmRNA, protein:increased expression:respiratory system fluid/secretion, macrophage PMID:23392573 REF_RGD_ID:8655969
Il18 ISOIl18 (Mus musculus)9068941RGD PMID:17400729 REF_RGD_ID:4889590
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