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GENE - TERM ANNOTATION REPORT

RGD ID: 18911181
Species: Heterocephalus glaber
RGD Object: Gene
Symbol: Rad50
Name: RAD50 double strand break repair protein
Acc ID: DOID:5426
Term: primary ovarian insufficiency
Definition: An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Premature_ovarian_failure "DO" "DO", https://pubmed.ncbi.nlm.nih.gov/27861765/ "DO" "DO", https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477642/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rad50 ISORAD50 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Premature ovarian insufficiencyPMID:16385572 PMID:25503501 PMID:25741868 PMID:26467025 PMID:28492532 PMID:30924587 PMID:31159747 PMID:31980526 PMID:32658311 PMID:33471991
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