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GENE - TERM ANNOTATION REPORT

RGD ID: 18662020
Species: Chlorocebus sabaeus
RGD Object: Gene
Symbol: POLR1A
Name: RNA polymerase I subunit A
Acc ID: GO:0003899
Term: DNA-directed 5'-3' RNA polymerase activity
Definition: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
Definition Source(s): EC:2.7.7.6, GOC:pf
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
POLR1Acontributes_toISOPolr1a (Rattus norvegicus)9068941RGD PMID:9422795 REF_RGD_ID:2312782
POLR1AenablesIEAUniProtKB:O95602 or ensembl:ENSP00000263857150520179Ensembl GO_REF:0000107
POLR1AenablesIEAInterPro:IPR000722 or InterPro:IPR006592 or InterPro:IPR007066 or InterPro:IPR007080 or InterPro:IPR007081 or InterPro:IPR007083 or InterPro:IPR045867150520179InterPro GO_REF:0000002
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