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GENE - TERM ANNOTATION REPORT

RGD ID: 1625089
Species: Homo sapiens
RGD Object: Gene
Symbol: FTO
Name: FTO alpha-ketoglutarate dependent dioxygenase
Acc ID: GO:0035515
Term: oxidative RNA demethylase activity
Definition: Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
Definition Source(s): PMID:12594517, PMID:16482161, PMID:18775698
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FTOenablesIEAUniProtKB:Q8BGW1 or ensembl:ENSMUSP00000068380150520179Ensembl GO_REF:0000107
FTOenablesIEAInterPro:IPR032868150520179InterPro GO_REF:0000002
FTOenablesIDA 150520179UniProt PMID:18775698 PMID:22002720 PMID:28002401 PMID:30197295

PMID:18775698 PMID:22002720 PMID:28002401 PMID:30197295
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