GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tslp | increases expression | EXP | | 6480464 | CTD | Toluene 2,4-Diisocyanate results in increased expression of TSLP mRNA; Toluene 2,4-Diisocyanate results in increased expression of TSLP protein | PMID:19647056 PMID:28329851 PMID:30017638 PMID:31577921 | Tslp | multiple interactions | EXP | | 6480464 | CTD | bisphenol A promotes the reaction [Toluene 2,4-Diisocyanate results in increased expression of and results in increased secretion of TSLP protein]; Estradiol promotes the reaction [Toluene 2,4-Diisocyanate results in increased expression of TSLP protein]; Methoxychlor promotes the reaction [Toluene 2,4-Diisocyanate results in increased expression of TSLP protein]; Toluene 2,4-Diisocyanate results in increased expression of and results in increased secretion of TSLP protein; TSLP protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL17A mRNA]; TSLP protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of RORC mRNA alternative form]; TSLP protein affects the reaction [Toluene 2,4-Diisocyanate results in increased secretion of IFNG protein]; TSLP protein affects the reaction [Toluene 2,4-Diisocyanate results in increased secretion of IL17A protein]; TSLP protein affects the reaction [Toluene 2,4-Diisocyanate results in increased secretion of IL4 protein]; TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of AGER protein]; TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of and results in increased phosphorylation of STAT5A protein]; TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of and results in increased phosphorylation of STAT5B protein]; TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of HMGB1 protein]; TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of TSLP protein]; TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased secretion of IFNG protein]; TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased secretion of IL13 protein]; TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased secretion of IL4 protein]; TSLP protein alternative form inhibits the reaction [Toluene 2,4-Diisocyanate results in increased secretion of IL5 protein] | PMID:28329851 PMID:29846729 PMID:30017638 PMID:31577921 | Tslp | increases secretion | ISO | TSLP (Homo sapiens) | 6480464 | CTD | Toluene 2,4-Diisocyanate results in increased secretion of TSLP protein | PMID:31577921 | | ||||||||||||||||||||||
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