GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pmaip1 | decreases expression | ISO | PMAIP1 (Homo sapiens) | 6480464 | CTD | pifithrin results in decreased expression of PMAIP1 protein | PMID:21810437 | Pmaip1 | multiple interactions | ISO | PMAIP1 (Homo sapiens) | 6480464 | CTD | pifithrin inhibits the reaction [[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] which results in increased expression of PMAIP1 protein]; pifithrin inhibits the reaction [goniothalamin results in increased expression of PMAIP1 protein]; pifithrin inhibits the reaction [Simvastatin results in increased expression of PMAIP1 mRNA] | PMID:20045437 PMID:21810437 PMID:35022897 | Pmaip1 | multiple interactions | ISO | Pmaip1 (Rattus norvegicus) | 6480464 | CTD | pifithrin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PMAIP1 protein] | PMID:33031904 | |
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