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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1621551
Species: Mus musculus
RGD Object: Gene
Symbol: Pmaip1
Name: phorbol-12-myristate-13-acetate-induced protein 1
Acc ID: CHEBI:229924
Term: pifithrin-?
Definition: null
Chemical ID: MESH:C121565
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pmaip1decreases expressionISOPMAIP1 (Homo sapiens)6480464CTDpifithrin results in decreased expression of PMAIP1 proteinPMID:21810437
Pmaip1multiple interactionsISOPMAIP1 (Homo sapiens)6480464CTDpifithrin inhibits the reaction [[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] which results in increased expression of PMAIP1 protein]; pifithrin inhibits the reaction [goniothalamin results in increased expression of PMAIP1 protein]; pifithrin inhibits the reaction [Simvastatin results in increased expression of PMAIP1 mRNA]PMID:20045437 PMID:21810437 PMID:35022897
Pmaip1multiple interactionsISOPmaip1 (Rattus norvegicus)6480464CTDpifithrin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PMAIP1 protein]PMID:33031904
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