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GENE - TERM ANNOTATION REPORT

RGD ID: 1620669
Species: Mus musculus
RGD Object: Gene
Symbol: Ank2
Name: ankyrin 2, brain
Acc ID: GO:0010881
Term: regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
Definition: Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
Definition Source(s): GOC:BHF, GOC:dph, GOC:tb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ank2involved_inICGO:00519242290270BHF-UCL MGI:2449848 PMID:12571597

MGI:2449848 PMID:12571597
Ank2involved_inIMP 2290270BHF-UCL MGI:5427070 PMID:21859974 MGI:5430893 PMID:17178715

MGI:5427070 MGI:5430893 PMID:17178715 PMID:21859974
Ank2involved_inISOUniProtKB:Q014842290270MGI GO_REF:0000119 MGI:4834177
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