GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gstp1 | affects export | ISO | GSTP1 (Homo sapiens) | 6480464 | CTD | GSTP1 gene SNP affects the export of Thiotepa | PMID:19076156 | Gstp1 | affects metabolic processing | ISO | GSTP1 (Homo sapiens) | 6480464 | CTD | GSTP1 gene polymorphism affects the metabolism of Thiotepa | PMID:10334868 | Gstp1 | affects response to substance | ISO | GSTP1 (Homo sapiens) | 6480464 | CTD | GSTP1 gene affects the susceptibility to Thiotepa; GSTP1 protein affects the susceptibility to Thiotepa | PMID:10334868 PMID:12360105 PMID:19076156 | Gstp1 | decreases response to substance | ISO | GSTP1 (Homo sapiens) | 6480464 | CTD | GSTP1 gene polymorphism results in decreased susceptibility to Thiotepa | PMID:10334868 | Gstp1 | increases metabolic processing | ISO | GSTP1 (Homo sapiens) | 6480464 | CTD | GSTP1 protein results in increased metabolism of Thiotepa | PMID:10334868 | Gstp1 | multiple interactions | ISO | GSTP1 (Homo sapiens) | 6480464 | CTD | GSTP1 gene affects the reaction [Glutathione affects the metabolism of Thiotepa]; GSTP1 protein affects the metabolism of [Thiotepa co-treated with Glutathione] | PMID:10334868 PMID:7712478 | |
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