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GENE - TERM ANNOTATION REPORT

RGD ID: 1619269
Species: Mus musculus
RGD Object: Gene
Symbol: H2-Aa
Name: histocompatibility 2, class II antigen A, alpha
Acc ID: DOID:437
Term: myasthenia gravis
Definition: An autoimmune disease of the nervous system that has_material_basis_in antibodies to acetylcholine receptors at the neuromuscular junction, has_symptom ptosis, has_symptom diplopia, has_symptom dysphagia, has_symptom dysarthria, has_symptom muscle weakness and has_symptom shortness of breath. (DO)
Definition Source(s): https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Myasthenia-Gravis-Fact-Sheet "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H2-Aa ISOHLA-DQA1 (Homo sapiens)5147855RGDDNA:polymorphisms, haplotype:cds:HLA-DQA!*0501, HLA-DQA1*0301 (human) 
H2-AasusceptibilityISOHLA-DQA1 (Homo sapiens)5147612RGDDNA:polymorphisms: :HLA-DQA1*0101/2, HLA-DQA1*0501 (human) 
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