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GENE - TERM ANNOTATION REPORT

RGD ID: 1618406
Species: Mus musculus
RGD Object: Gene
Symbol: Scx
Name: scleraxis scleraxis bHLH transcription factor
Acc ID: GO:0035990
Term: tendon cell differentiation
Definition: The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.
Definition Source(s): CL:0000388, GOC:yaf, PMID:21412429
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scxinvolved_inIMP 2290270UniProt MGI:3715390 PMID:17567668 MGI:4418577 PMID:20059955

MGI:3715390 MGI:4418577 PMID:17567668 PMID:20059955
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