GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cxcl15 | increases expression | EXP | | 6480464 | CTD | arsenite results in increased expression of CXCL5 mRNA | PMID:18929588 | Cxcl15 | multiple interactions | EXP | | 6480464 | CTD | TRP53 protein affects the reaction [arsenite results in increased expression of CXCL5 mRNA] | PMID:18929588 | Cxcl15 | affects expression | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | arsenite affects the expression of CXCL8 mRNA | PMID:22959463 | Cxcl15 | decreases expression | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | arsenite results in decreased expression of CXCL8 mRNA | PMID:16085347 | Cxcl15 | increases expression | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | arsenite results in increased expression of CXCL8 mRNA; arsenite results in increased expression of CXCL8 protein | PMID:18418899 PMID:25257954 | Cxcl15 | multiple interactions | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | [arsenite results in increased activity of [NFKB1 protein binds to RELB protein]] which results in increased expression of CXCL8 mRNA; arsenite inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; arsenite promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 mRNA]; arsenite promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CXCL8 protein]; caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of CXCL8 mRNA] | PMID:10775461 PMID:16085347 PMID:18418899 PMID:25680285 | |
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