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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1617608
Species: Mus musculus
RGD Object: Gene
Symbol: Cxcl15
Name: C-X-C motif chemokine ligand 15
Acc ID: CHEBI:28741
Term: sodium fluoride
Definition: A metal fluoride salt with a Na(+) counterion.
Chemical ID: MESH:D012969
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl15decreases expressionEXP 6480464CTDSodium Fluoride results in decreased expression of CXCL5 mRNAPMID:21340527
Cxcl15increases expressionISOCXCL8 (Homo sapiens)6480464CTDSodium Fluoride results in increased expression of CXCL8 mRNAPMID:25540590
Cxcl15increases secretionISOCXCL8 (Homo sapiens)6480464CTDSodium Fluoride results in increased secretion of CXCL8 proteinPMID:25540590
Cxcl15multiple interactionsISOCXCL8 (Homo sapiens)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sodium Fluoride results in increased secretion of CXCL8 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Sodium Fluoride results in increased secretion of CXCL8 protein]; Curcumin inhibits the reaction [Sodium Fluoride results in increased secretion of CXCL8 protein]; pyrazolanthrone inhibits the reaction [Sodium Fluoride results in increased secretion of CXCL8 protein]; RELA protein affects the reaction [Sodium Fluoride results in increased secretion of CXCL8 protein]PMID:25540590
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