GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cxcl15 | increases abundance | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | CXCL8 protein results in increased abundance of Calcium | PMID:15748943 | Cxcl15 | increases uptake | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | CXCL8 protein results in increased uptake of Calcium | PMID:10984371 | Cxcl15 | multiple interactions | ISO | CXCL8 (Homo sapiens) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; [CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein; Calcium promotes the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; CXCL8 protein affects the localization of and affects the abundance of Calcium; resveratrol inhibits the reaction [CXCL8 protein affects the localization of Calcium] | PMID:11298490 PMID:14505796 PMID:15528384 PMID:16212921 PMID:17000667 | | ||||||||||||||||||||||
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