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GENE - TERM ANNOTATION REPORT

RGD ID: 1617311
Species: Mus musculus
RGD Object: Gene
Symbol: Lgi4
Name: leucine-rich repeat LGI family, member 4
Acc ID: GO:0022011
Term: myelination in peripheral nervous system
Definition: The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
Definition Source(s): GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lgi4involved_inIBAPANTHER:PTN002519797 or MGI:21801972290270GO_Central GO_REF:0000033
Lgi4acts_upstream_of_or_withinIMPMGI:18565942290270MGI PMID:1652607 PMID:9671673

PMID:1652607 PMID:9671673
Lgi4acts_upstream_of_or_withinIMPMGI:4359600 and MGI:44413112290270MGI PMID:20220021

PMID:20220021
Lgi4acts_upstream_of_or_withinIMPMGI:44392692290270MGI PMID:21068328

PMID:21068328
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