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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1615570
Species: Mus musculus
RGD Object: Gene
Symbol: Syne2
Name: spectrin repeat containing, nuclear envelope 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Syne2affects expressionISOSyne2 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of SYNE2 mRNAPMID:25181051
Syne2decreases expressionISOSyne2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of SYNE2 mRNAPMID:30816183 PMID:34947998
Syne2decreases expressionISOSYNE2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of SYNE2 proteinPMID:33376534 PMID:37567409
Syne2increases methylationISOSYNE2 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of SYNE2 genePMID:31601247
Syne2multiple interactionsISOSYNE2 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of SYNE2 genePMID:31601247
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