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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1614799
Species: Mus musculus
RGD Object: Gene
Symbol: Slc47a2
Name: solute carrier family 47, member 2
Acc ID: CHEBI:77733
Term: 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile
Definition: A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Chemical ID: MESH:D014700
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc47a2decreases activityISOSLC47A2 (Homo sapiens)6480464CTDVerapamil results in decreased activity of SLC47A2 proteinPMID:28629854 PMID:31364238
Slc47a2multiple interactionsISOSLC47A2 (Homo sapiens)6480464CTDVerapamil inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Verapamil inhibits the reaction [SLC47A2 protein results in increased uptake of Tetraethylammonium]PMID:22419765 PMID:27989701
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