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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1614463
Species: Mus musculus
RGD Object: Gene
Symbol: Csf2rb2
Name: colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csf2rb2affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of CSF2RB2 mRNA

PMID:26377647, PMID:28922406
Csf2rb2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of CSF2RB mRNA, Tetrachlorodibenzodioxin results in increased expression of CSF2RB protein, Tetrachlorodibenzodioxin results in increased expression of CSF2RB2 mRNA

PMID:11879969, PMID:16891777, PMID:19770486
Csf2rb2multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSF2RB2 mRNA, AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CSF2RB2 mRNA]

PMID:16891777, PMID:17942748
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.