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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1614446
Species: Mus musculus
RGD Object: Gene
Symbol: Mycn
Name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mycndecreases expressionEXP 6480464CTDTretinoin results in decreased expression of MYCN mRNAPMID:16604517
Mycndecreases expressionISOMYCN (Homo sapiens)6480464CTDTretinoin results in decreased expression of MYCN; Tretinoin results in decreased expression of MYCN mRNAPMID:17229153 PMID:17283129 PMID:17486130 PMID:23724009
Mycnmultiple interactionsISOMYCN (Homo sapiens)6480464CTDR116010 promotes the reaction [Tretinoin results in decreased expression of MYCN mRNA]PMID:17486130
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