Gene Term Annotation Report - Rat Genome Database

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GENE - TERM ANNOTATION REPORT

RGD ID:	1610420
Species:	Mus musculus
RGD Object:	Gene
Symbol:	H2-Q4
Name:	histocompatibility 2, Q region locus 4

Acc ID:	DOID:13141
Term:	uveitis
Definition:	An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid. (DO)
Definition Source(s):	https://www.mayoclinic.org/diseases-conditions/uveitis/symptoms-causes/syc-20378734 "DO" "DO"

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
H2-Q4		ISO	HLA-B (Homo sapiens)	7364926	RGD	associated with Inflammatory Bowel Diseases; DNA:polymorphisms:cds:HLA-B27, HLA-B58 (human)
H2-Q4	onset	ISO	HLA-B (Homo sapiens)	7364788	RGD	associated with Behcet Syndrome; DNA:polymorphisms:cds:HLA-B*51 (human)
H2-Q4	treatment	ISO	HLA-B (Homo sapiens)	7364942	RGD

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