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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1608325
Species: Mus musculus
RGD Object: Gene
Symbol: Mir148a
Name: microRNA 148a
Acc ID: CHEBI:41879
Term: dexamethasone
Definition: A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
Chemical ID: MESH:D003907
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir148aincreases expressionISOMIR148A (Homo sapiens)6480464CTDDexamethasone results in increased expression of MIR148A mRNAPMID:32234517
Mir148aincreases expressionISOMir148a (Rattus norvegicus)6480464CTDDexamethasone results in increased expression of MIR148A mRNAPMID:32234517
Mir148amultiple interactionsISOMIR148A (Homo sapiens)6480464CTDMifepristone inhibits the reaction [Dexamethasone results in increased expression of MIR148A mRNA]; MIR148A mRNA affects the reaction [Dexamethasone results in decreased expression of LDLR mRNA]; MIR148A mRNA affects the reaction [Dexamethasone results in decreased expression of LDLR protein]PMID:32234517
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