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GENE - TERM ANNOTATION REPORT

RGD ID: 1607089
Species: Homo sapiens
RGD Object: Gene
Symbol: GBA1
Name: glucosylceramidase beta 1
Acc ID: DOID:9000495
Term: Tremor
Definition: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.
Definition Source(s): MESH:D014202
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GBA1 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Resting tremorPMID:10649495 PMID:10714667 PMID:10796875 PMID:11336129 PMID:14757438 PMID:15146461 PMID:15605411 PMID:16293621 PMID:16967369 PMID:17427031 PMID:17620502 PMID:17875915 PMID:18022370 PMID:18332251 PMID:18338393 PMID:18347322 PMID:18541817 PMID:18987351 PMID:1899336 PMID:19286695 PMID:1972019 PMID:20004703 PMID:20301446 PMID:20816920 PMID:21106416 PMID:21228398 PMID:21472771 PMID:21700212 PMID:21700325 PMID:21742527 PMID:21745757 PMID:21856586 PMID:22006919 PMID:22160715 PMID:22192918 PMID:22220748 PMID:22227073 PMID:22623374 PMID:22713811 PMID:22975760 PMID:2309702 PMID:23227814 PMID:23277556 PMID:23286447 PMID:23430543 PMID:23448517 PMID:23588557 PMID:23635853 PMID:23676350 PMID:23719189 PMID:2378352 PMID:24020503 PMID:24022302 PMID:24095219 PMID:24126159 PMID:24195576 PMID:24522292 PMID:2464926 PMID:25249066 PMID:25333069 PMID:25535748 PMID:2569551 PMID:25741868 PMID:25741914 PMID:26096741 PMID:27014572 PMID:27094865 PMID:27123474 PMID:27153395 PMID:27717005 PMID:27865684 PMID:27896091 PMID:28492532 PMID:28546865 PMID:28686011 PMID:28727984 PMID:2880291 PMID:28894968 PMID:28947706 PMID:28969384 PMID:29029963 PMID:29471591 PMID:29487000 PMID:29602947 PMID:29625627 PMID:29934114 PMID:30146349 PMID:30285649 PMID:30456712 PMID:30548430 PMID:30606667 PMID:30662625 PMID:30941926 PMID:31010158 PMID:31130284 PMID:31216804 PMID:31561936 PMID:32014045 PMID:32618053 PMID:32714263 PMID:32883051 PMID:33083013 PMID:33176831 PMID:33402667 PMID:33473340 PMID:33763395 PMID:33897756 PMID:33977031 PMID:34073924 PMID:34275192 PMID:7981693 PMID:8160756 PMID:8294487 PMID:8929950 PMID:9375849
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