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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1607085
Species: Homo sapiens
RGD Object: Gene
Symbol: SLCO1A2
Name: solute carrier organic anion transporter family member 1A2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLCO1A2affects expressionISOSlco1a5 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLCO1A5 mRNAPMID:21570461
SLCO1A2affects expressionISOSlco1a4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLCO1A4 mRNAPMID:22298810
SLCO1A2decreases expressionISOSlco1a5 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLCO1A5 mRNAPMID:33956508
SLCO1A2decreases expressionISOSlco1a4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLCO1A2 mRNA; Tetrachlorodibenzodioxin results in decreased expression of SLCO1A4 mRNAPMID:16054898 PMID:18178546 PMID:18796159 PMID:20558275 PMID:20959002 PMID:21724226 PMID:22808131
SLCO1A2increases expressionISOSlco1a4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SLCO1A4 mRNAPMID:22659317
SLCO1A2multiple interactionsISOSlco1a5 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of SLCO1A5 mRNAPMID:19465110
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