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GENE - TERM ANNOTATION REPORT

RGD ID: 1606722
Species: Homo sapiens
RGD Object: Gene
Symbol: TMPRSS11B
Name: transmembrane serine protease 11B
Acc ID: GO:0004252
Term: serine-type endopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Definition Source(s): GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TMPRSS11BenablesIEAInterPro:IPR001254 or InterPro:IPR017329 or InterPro:IPR018114150520179InterPro GO_REF:0000002
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