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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1606587
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP19A1
Name: cytochrome P450 family 19 subfamily A member 1
Acc ID: CHEBI:79516
Term: Nonylphenol
Definition: null
Chemical ID: MESH:C025256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP19A1decreases activityEXP 6480464CTDnonylphenol results in decreased activity of CYP19A1 proteinPMID:17599374
CYP19A1increases activityEXP 6480464CTDnonylphenol results in increased activity of CYP19A1 proteinPMID:27825933
CYP19A1multiple interactionsEXP 6480464CTD[Dichlorodiphenyl Dichloroethylene co-treated with nonylphenol] results in increased activity of CYP19A1 protein; bis(tri-n-butyltin)oxide promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]; bisphenol A promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]; Chlordecone promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]; nonylphenol promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]; nonylphenol promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]; nonylphenol promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]PMID:17599374
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