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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1606587
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP19A1
Name: cytochrome P450 family 19 subfamily A member 1
Acc ID: CHEBI:5870
Term: imidacloprid
Definition: An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1.
Chemical ID: MESH:C082359
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP19A1affects expressionEXP 6480464CTDimidacloprid affects the expression of CYP19A1 mRNAPMID:29701941
CYP19A1increases activityEXP 6480464CTDimidacloprid results in increased activity of CYP19A1 proteinPMID:28750898
CYP19A1multiple interactionsEXP 6480464CTD1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione affects the reaction [imidacloprid affects the expression of CYP19A1 mRNA]PMID:29701941
CYP19A1decreases expressionISOCyp19a1 (Rattus norvegicus)6480464CTDimidacloprid results in decreased expression of CYP19A1 mRNAPMID:34171690
CYP19A1multiple interactionsISOCyp19a1 (Rattus norvegicus)6480464CTDThymol inhibits the reaction [imidacloprid results in decreased expression of CYP19A1 mRNA]PMID:34171690
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