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GENE - TERM ANNOTATION REPORT

RGD ID: 1606184
Species: Homo sapiens
RGD Object: Gene
Symbol: XKR4
Name: XK related 4
Acc ID: GO:0070782
Term: phosphatidylserine exposure on apoptotic cell surface
Definition: A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.
Definition Source(s): GOC:mah, GOC:mtg_apoptosis, GOC:rk, PMID:11536005
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
XKR4involved_inIBAMGI:2685877 or MGI:2686466 or MGI:3528744 or PANTHER:PTN000411029 or UniProtKB:Q5GH76 or UniProtKB:Q9H6D3 or WB:WBGene00000422150520179GO_Central GO_REF:0000033
XKR4involved_inIEAPANTHER:PTHR16024:SF16150520179TreeGrafter GO_REF:0000118
XKR4involved_inIDA 150520179UniProt PMID:33725486

PMID:33725486
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