Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605729
Species: Homo sapiens
RGD Object: Gene
Symbol: HMGB1
Name: high mobility group box 1
Acc ID: CHEBI:33128
Term: C60 fullerene
Definition: A fullerene that has formula C60.
Chemical ID: MESH:C069837
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMGB1increases secretionISOHmgb1 (Mus musculus)6480464CTDfullerene C60 results in increased secretion of HMGB1 proteinPMID:31504961
HMGB1multiple interactionsISOHmgb1 (Mus musculus)6480464CTD2',3'-dialdehyde ATP inhibits the reaction [fullerene C60 results in increased secretion of HMGB1 protein]; [[fullerene C60 results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein] which results in increased expression of RAC1 protein; [fullerene C60 results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein; Adenosine Triphosphate promotes the reaction [fullerene C60 results in increased secretion of HMGB1 protein]; fullerene C60 results in increased localization of and results in increased secretion of HMGB1 protein; P2RX7 protein affects the reaction [fullerene C60 results in increased secretion of HMGB1 protein]PMID:31504961
Go Back to source page   Continue to Ontology report