GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HMGB1 | increases secretion | ISO | Hmgb1 (Mus musculus) | 6480464 | CTD | fullerene C60 results in increased secretion of HMGB1 protein | PMID:31504961 | HMGB1 | multiple interactions | ISO | Hmgb1 (Mus musculus) | 6480464 | CTD | 2',3'-dialdehyde ATP inhibits the reaction [fullerene C60 results in increased secretion of HMGB1 protein]; [[fullerene C60 results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein] which results in increased expression of RAC1 protein; [fullerene C60 results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein; Adenosine Triphosphate promotes the reaction [fullerene C60 results in increased secretion of HMGB1 protein]; fullerene C60 results in increased localization of and results in increased secretion of HMGB1 protein; P2RX7 protein affects the reaction [fullerene C60 results in increased secretion of HMGB1 protein] | PMID:31504961 | |
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