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GENE - TERM ANNOTATION REPORT

RGD ID: 1605413
Species: Homo sapiens
RGD Object: Gene
Symbol: IFT140
Name: intraflagellar transport 140
Acc ID: GO:0036064
Term: ciliary basal body
Definition: A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodeling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
Definition Source(s): GOC:cilia, GOC:clt, PMID:21750193
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IFT140located_inIEAUniProtKB:E9PY46 or ensembl:ENSMUSP00000024983150520179Ensembl GO_REF:0000107
IFT140is_active_inIBAMGI:2146906 or PANTHER:PTN000404360 or UniProtKB:A0A644F0T7 or UniProtKB:A8BAF1 or UniProtKB:A8BJ87 or UniProtKB:Q96RY7150520179GO_Central GO_REF:0000033
IFT140located_inIEAPANTHER:PTHR15722:SF7150520179TreeGrafter GO_REF:0000118
IFT140located_inIDA 150520179UniProt PMID:22503633

PMID:22503633
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