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GENE - TERM ANNOTATION REPORT

RGD ID: 1604194
Species: Homo sapiens
RGD Object: Gene
Symbol: RICTOR
Name: RPTOR independent companion of MTOR complex 2
Acc ID: GO:0031932
Term: TORC2 complex
Definition: A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.
Definition Source(s): GOC:bf, GOC:jh, PMID:14736892, PMID:15780592, PMID:16469695, PMID:21548787
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RICTORlocated_inIPI 150520179ComplexPortal PMID:17461779

PMID:17461779
RICTORpart_ofIEAUniProtKB:Q6QI06 or ensembl:ENSMUSP00000051809150520179Ensembl GO_REF:0000107
RICTORpart_ofIBAFB:FBgn0031006 or MGI:1926007 or PANTHER:PTN000329282 or PomBase:SPBC12C2.02c or SGD:S000000895 or UniProtKB:Q6R327 or WB:WBGene00009245 or dictyBase:DDB_G0277399150520179GO_Central GO_REF:0000033
RICTORpart_ofIEAInterPro:IPR028268150520179InterPro GO_REF:0000002
RICTORpart_ofIEAPANTHER:PTHR13298:SF11150520179TreeGrafter GO_REF:0000118
RICTORpart_ofIDA 150520179UniProt PMID:15268862 PMID:15467718 PMID:24036451

PMID:15268862 PMID:15467718 PMID:24036451
RICTORpart_ofIEAARBA:ARBA00026254150520179UniProt GO_REF:0000117
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