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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1604061
Species: Homo sapiens
RGD Object: Gene
Symbol: CCL5
Name: C-C motif chemokine ligand 5
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL5multiple interactionsEXP 6480464CTD[Copper co-treated with Hydrogen Peroxide] promotes the reaction [CCL5 protein binds to CCL5 protein]; [Copper co-treated with Hydrogen Peroxide] results in increased activity of CCL5 protein; [Disulfiram binds to Copper] which results in increased expression of CCL5 mRNAPMID:21963154 PMID:24690739
CCL5increases secretionISOCcl5 (Mus musculus)6480464CTDCopper results in increased secretion of CCL5 proteinPMID:19635393
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