GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CCR2 | decreases response to substance | ISO | Ccr2 (Mus musculus) | 6480464 | CTD | CCR2 gene mutant form results in decreased susceptibility to Bleomycin | PMID:14609568 | CCR2 | increases expression | ISO | Ccr2 (Mus musculus) | 6480464 | CTD | Bleomycin results in increased expression of CCR2 mRNA | PMID:29033951 | CCR2 | multiple interactions | ISO | Ccr2 (Mus musculus) | 6480464 | CTD | CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA] | PMID:14609568 | | ||||||||||||||||||||||
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