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GENE - TERM ANNOTATION REPORT

RGD ID: 1603048
Species: Homo sapiens
RGD Object: Gene
Symbol: PAM16
Name: presequence translocase associated motor 16
Acc ID: GO:0030150
Term: protein import into mitochondrial matrix
Definition: The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.
Definition Source(s): ISBN:0716731363
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAPANTHER:PTN000273250, SGD:S000003640, UniProtKB:Q9Y3D72290271GO_Central (PMID:21873635)

PMID:21873635
 IEAInterPro:IPR0053412290271InterPro GO_REF:0000002
 IGISGD:S0000036402290271GO_Central (PMID:20053669)

PMID:20053669
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.