GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IDO2 | decreases expression | ISO | Ido2 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of IDO2 mRNA | PMID:27339419 PMID:31919559 | IDO2 | decreases expression | ISO | Ido2 (Rattus norvegicus) | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of IDO2 mRNA | PMID:31150632 | IDO2 | increases expression | ISO | Ido2 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of IDO2 mRNA | PMID:32289347 | IDO2 | multiple interactions | ISO | Ido2 (Mus musculus) | 6480464 | CTD | IDO2 gene mutant form inhibits the reaction [Carbon Tetrachloride affects the localization of and results in increased activity of AHR protein]; IDO2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased abundance of Kynurenine]; IDO2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; IDO2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased secretion of TNF protein]; IDO2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP1A1 mRNA]; IDO2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA]; IDO2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; Kynurenine inhibits the reaction [IDO2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP1A1 mRNA]] | PMID:32289347 | IDO2 | multiple interactions | ISO | Ido2 (Rattus norvegicus) | 6480464 | CTD | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of IDO2 mRNA] | PMID:31150632 | | ||||||||||||||||||||||
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