GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ngf | decreases expression | EXP | | 6480464 | CTD | Cyclophosphamide results in decreased expression of NGF protein | PMID:10683293 | Ngf | increases expression | EXP | | 6480464 | CTD | Cyclophosphamide results in increased expression of NGF mRNA; Cyclophosphamide results in increased expression of NGF protein | PMID:10683293 PMID:16879691 PMID:32615180 | Ngf | multiple interactions | EXP | | 6480464 | CTD | NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]; rofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein] | PMID:16879691 PMID:19996110 PMID:32615180 | Ngf | increases expression | ISO | Ngf (Mus musculus) | 6480464 | CTD | Cyclophosphamide results in increased expression of NGF protein | PMID:18299998 PMID:20127836 | Ngf | multiple interactions | ISO | Ngf (Mus musculus) | 6480464 | CTD | 3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazoleacetic acid methyl ester inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]; Cyclophosphamide promotes the reaction [NGF results in increased expression of VEGFA mRNA]; VIP protein affects the reaction [Cyclophosphamide results in increased expression of NGF protein] | PMID:18299998 PMID:18632792 PMID:20127836 | | ||||||||||||||||||||||
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