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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1597189
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pnp
Name: purine nucleoside phosphorylase
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pnpmultiple interactionsISOPNP (Homo sapiens)6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PNP mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of PNP mRNA; [Volatile Organic Compounds co-treated with Ozone] results in decreased expression of PNP mRNAPMID:32699268
Pnpmultiple interactionsISOPnp2 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of PNP2 mRNAPMID:34911549
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