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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: RT1-Ba
Name: RT1 class II, locus Ba
Acc ID: CHEBI:34202
Term: 2,2',4,4',5,5'-hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C014024
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RT1-Baaffects expressionISOHLA-DQA1 (Homo sapiens)6480464CTD2,4,5,2',4',5'-hexachlorobiphenyl affects the expression of HLA-DQA1 mRNAPMID:20638727
RT1-Bamultiple interactionsISOH2-Aa (Mus musculus)6480464CTD[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of H2-AA mRNAPMID:25510870
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