GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atm | decreases expression | ISO | Atm (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of ATM mRNA | PMID:31919559 | Atm | multiple interactions | ISO | Atm (Mus musculus) | 6480464 | CTD | ATM mRNA inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased secretion of TGFB1 protein]; ATM protein inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]; ATM protein inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; ATM protein inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX protein]; ATM protein inhibits the reaction [Carbon Tetrachloride results in increased expression of MKI67 protein]; ATM protein inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of H2AX protein]; ATM protein promotes the reaction [Carbon Tetrachloride results in increased expression of BCL2 protein]; ATM protein promotes the reaction [Carbon Tetrachloride results in increased phosphorylation of CDC25A protein]; ATM protein promotes the reaction [Carbon Tetrachloride results in increased phosphorylation of CDC25C protein]; ATM protein promotes the reaction [Carbon Tetrachloride results in increased phosphorylation of CHEK2 protein] | PMID:36526012 | | ||||||||||||||||||||||
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