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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1592345
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mt2A
Name: metallothionein 2A
Acc ID: CHEBI:34342
Term: 3-methylcholanthrene
Definition: A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Chemical ID: MESH:D008748
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mt2Aincreases expressionISOMT2A (Homo sapiens)6480464CTDMethylcholanthrene results in increased expression of MT2A mRNAPMID:23994556
Mt2Amultiple interactionsISOMT2A (Homo sapiens)6480464CTDAHR protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]; NR3C1 protein affects the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]PMID:23994556
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