GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mpo | increases response to substance | ISO | Mpo (Mus musculus) | 6480464 | CTD | MPO protein results in increased susceptibility to Mechlorethamine | PMID:24631667 | Mpo | multiple interactions | ISO | Mpo (Mus musculus) | 6480464 | CTD | MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of MMP9]; MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of NOS2]; MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of PTGS2] | PMID:24631667 | | ||||||||||||||||||||||
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