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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589741
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rgs16
Name: regulator of G-protein signaling 16
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rgs16decreases expressionISORGS16 (Homo sapiens)6480464CTDTretinoin results in decreased expression of RGS16 mRNAPMID:15498508 PMID:16129123 PMID:21934132 PMID:33167477
Rgs16increases expressionISORGS16 (Homo sapiens)6480464CTDTretinoin results in increased expression of RGS16 mRNAPMID:16012519 PMID:23724009
Rgs16multiple interactionsISORgs16 (Mus musculus)6480464CTD[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RGS16 mRNAPMID:36189433
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