GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Eif2a | decreases response to substance | ISO | EIF2A (Homo sapiens) | 6480464 | CTD | EIF2A protein results in decreased susceptibility to nonivamide | PMID:17332266 | Eif2a | increases phosphorylation | ISO | EIF2A (Homo sapiens) | 6480464 | CTD | nonivamide results in increased phosphorylation of EIF2A protein | PMID:17332266 | Eif2a | multiple interactions | ISO | EIF2A (Homo sapiens) | 6480464 | CTD | [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of EIF2A protein; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased phosphorylation of EIF2A protein; salubrinal inhibits the reaction [EIF2A protein results in decreased susceptibility to nonivamide] | PMID:17332266 | |
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