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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1588534
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lpin3
Name: lipin 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lpin3increases expressionEXP 6480464CTDbisphenol A results in increased expression of LPIN3 mRNAPMID:25181051
Lpin3increases methylationISOLpin3 (Mus musculus)6480464CTDbisphenol A results in increased methylation of LPIN3 promoterPMID:27312807
Lpin3multiple interactionsISOLpin3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of LPIN3 mRNAPMID:28433925
Lpin3multiple interactionsISOLPIN3 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of LPIN3 genePMID:31601247
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