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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1587662
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmut
Name: methylmalonyl-CoA mutase
Acc ID: CHEBI:42768
Term: geneticin
Definition: An aminoglycoside antibiotic produced by Micromonospora rhodorangea. It blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
Chemical ID: MESH:C010680
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmutaffects expressionISOMMUT (Homo sapiens)6480464CTDantibiotic G 418 affects the expression of MMUT mRNA mutant formPMID:19427250
Mmutmultiple interactionsISOMMUT (Homo sapiens)6480464CTD[antibiotic G 418 co-treated with Gentamicins] affects the activity of MMUT protein mutant form; [antibiotic G 418 co-treated with Gentamicins] affects the expression of MMUT mRNA mutant form; antibiotic G 418 promotes the reaction [Gentamicins affects the expression of MMUT protein mutant form]PMID:19427250
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