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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1587390
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkg1
Name: protein kinase cGMP-dependent 1
Acc ID: CHEBI:38725
Term: mevinphos
Definition: An organophosphate insecticide that has formula C7H13O6P.
Chemical ID: MESH:D008799
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDMevinphos results in increased expression of PRKG1 mRNA, Mevinphos results in increased expression of PRKG1 protein

PMID:15617736, PMID:28601397
multiple interactionsEXP 6480464CTD1H-(1, 2, 4)oxadiazolo(4, 3-a)quinoxalin-1-one inhibits the reaction [Mevinphos results in increased expression of PRKG1 protein], 7-nitroindazole inhibits the reaction [Mevinphos results in increased expression of PRKG1 protein]

PMID:15617736
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.